Publications 

 

 2016

Werden S.J., Sphyris N., Sarkar T.R., Paranjape A.N., LaBaff A.M., Taube J.H., Hollier B.G., Ramirez-Peña E.Q., Soundararajan R., den Hollander P., Powell E., Echeverria G.V., Miura N., Chang J.T., Piwnica-Worms H., Rosen J.M., and Mani S.A., Phosphorylation of serine 367 of FOXC2 by p38 regulates ZEB1 and breast cancer metastasis, without impacting primary tumor growth, Oncogene (2016) 

SvanidzeE., Besara T., Ozaydin M., Tiwary C., Wang J.K., Radhakrishnan S., Mani S.A., Xin Y., Han K., Liang H., Siegrist T., Ajayan P.M., and Morosan E., High hardness in the biocompatible intermetallic compound β-Ti3AuScience Advances  20 Jul 2016:2 (7), e1600319 DOI: 10.1126/sciadv.1600319

Kwon O.J., Zhang L., Wang J., Su Q., Feng Q., Zhang X.H., Mani S.A., Paulter R., Creighton C.J., Ittmann M.M., Xin L., Notch promotes tumor metastasis in a prostate-specific Pten-null mouse model. The Journal of clinical investigation. 2016; 126(7):2626-41. PubMed [journal]PMID: 27294523 PMCID: PMC4922719. 

Toneff M.J., Sreekumar A., Tinnirello A., Hollander P.D., Habib S., Li S., Ellis M.J., Xin L., Mani S.A., Rosen J.M., The Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states. BMC biology. 2016; 14(1):47. PubMed [journal]PMID: 27317311 PMCID: PMC4912796. 

Ashokkumar M., Cristian Chipara A., Tharangattu Narayanan N., Anumary A., Sruthi R., Thanikaivelan P., Vajtai R.,Mani S.A., Ajayan P.M., Three-Dimensional Porous Sponges from Collagen Biowastes. ACS applied materials & interfaces. 2016; 8(23):14836-44. PubMed [journal]PMID: 27219483.

Boareto M., Jolly M.K., Goldman A., Pietilä M., Mani S.A., Sengupta S., Ben-Jacob E., Levine H., Onuchic J.N., Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype. Journal of the Royal Society, Interface / the Royal Society. 2016; 13(118). PubMed [journal]PMID: 27170649 PMCID: PMC4892257.

Pietilä M., Vijay G.V., Soundararajan R., Yu X., Symmans W.F., Sphyris N., Mani S.A., FOXC2 regulates the G2/M transition of stem cell-rich breast cancer cells and sensitizes them to PLK1 inhibition, Sci. Rep (2016)

Jolly M.K., Tripathi S.C., Jia D., Mooney S.M., Celiktas M., Hanash S.M., Mani S.A., Pienta K.J., Ben-Jacob E., Levine H., Stability of the hybrid epithelial/mesenchymal phenotype, Oncotarget (2016)

Paranjape A., Soundararajan R., Werden S.J., Joseph R., Taube J.H., Liu H., Rodriguez-Canales J., Sphyris N., Wistuba, I.I., Dhillon J., Mahajan N., Mahajan K., Chang J., Ittmann M., Maity S., Logothetis, C., Miura, N., Tang, D.,Mani S.A., Inhibition of FOXC2 restores epithelial phenotype and drug-sensitivity in prostate cancer cells with stem-like properties, Oncogene 2016

Zhao W., Prijic S., Urban B.C., Tisza M.J., Zuo Y., Li L., Tan Z., Chen X., Mani S.A., Chang J.T., Candidate anti-metastasis drugs suppress the metastatic capacity of breast cancer cells by reducing membrane fluidity, Can Res 2016

Dhawan A., Tonekaboni S. A. M., Taube J.H., Stephen Hu S., Sphyris N., Mani S.A.*, & Kohandel M.*, Mathematicalmodeling of phenotypic plasticity and conversion to a stem-cell state under hypoxia, Scientific Reports 2016 (*co-corresponding authors)

 

2015

Jolly MK, Jia D., Boareto M, Mani S.A., Pienta K.J., Ben-Jacob E., Levine H, Coupling the modules of EMT and stemness: A tunable ‘stemness window’ model. Oncotarget 2015.

Bhowmik SK, Ramirez-Peña E, Arnold JM, Putluri V, Sphyris N, Michailidis G, Putluri N, Ambs S, Sreekumar A,Mani S.A., EMT-Induced Metabolite Signature Identifies Poor Clinical Outcome. Oncotarget. e-Pub 7/2015. PMID: 26315396.

Soundararajan R, Paranjape AN, Barsan V, Chang JT, Mani S.A., A novel embryonic plasticity gene signature that predicts metastatic competence and clinical outcome. Scientific Reports 5:11766, 2015. e-Pub 6/2015. PMCID: PMC4485318.

Mallampati S, Leng X, Ma H, Zeng J, Li J, Wang H, Lin K, Lu Y, Yang Y, Sun B, Gong Y, Lee JS, Konopleva M, Andreeff M, Arlinghaus RB, Cai Z, Fang B, Shen H, Han X, Hirsch-Ginsberg CF, Gao X, Paranjape AN, Mani S.A., Clise-Dwyer K, Sun X. Tyrosine kinase inhibitors induce mesenchymal stem cell-mediated resistance in BCR-ABL+ acute lymphoblastic leukemia. Blood. e-Pub 2/2015. PMID: 25712988.

Jolly MK, Huang B, Lu M, Mani S.A., Levine H, Ben-Jacob E. Towards elucidating the connection between epithelial-mesenchymal transitions and stemness. J R Soc Interface 11(101):20140962.

2014

Sarkar TR, Battula VL, Werden SJ, Vijay GV, Ramirez-Peña EQ, Taube JH, Chang JT, Miura N, Porter W,  Sphyris N, Andreeff M, Mani S.A., GD3 synthase regulates epithelial-mesenchymal transition and metastasis in breast cancer.Oncogene, 2014 Aug 11;0. doi: 10.1038/onc.2014.245

Krohn, A., Ahrens T.,  Yalcin A., Plönes T., Wehrle J., Taromi S., Wollner S., Follo M., Brabletz T., Mani S.A., Claus R., Hackanson B., Burger M., Tumor Cell Heterogeneity in Small Cell Lung Cancer (SCLC): Phenotypical and Functional Differences Associated with Epithelial-Mesenchymal Transition (EMT) and DNA Methylation Changes.PLOS ONE 2014 9(6) e100249

2013

Malouf G.G., Taube J.H., Lu Y., Roysarkar T., Panjarian S., Estecio M.R., Jelinek J., Yamazaki J., Raynal N.J., Long H., Tahara T., Tinnirello A., Ramachandran P., Zhang X.Y., Liang S., Mani S.A.*, Issa J.P.*, Architecture of epigenetic reprogramming following Twist1 mediated epithelial-mesenchymal transition. Genome Biol. 2013 Dec24;14(12): R144  (*co-corresponding authors)

Liu, Y., Zhou, R., Baumbusch, L.O., Tsavachidis, S., Brewster, A.M., Do, K.-A., Sahin, A., Hortobagyi, G.N., Taube, J.H., Mani, S.A., Aarøe, J., Wärnberg, F., Børresen-Dale, A.-L., Mills, G.B., Thompson, P.A. , Bondy, M.L.  Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer, Breast Cancer Research and Treatment 2013, Pages 1-13 

Taube J.H., Malouf G.G., Lu E., Sphyris N., Vijay V., Ramachandran P.R., Ueno K.R., Gaur S., Nicoloso M.S., Rossi S., Herschkowitz J.I., Rosen J.M., Issa J.J., Calin G.A., Chang J.T., Mani S.A., Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties. Scientific Reports. 3, 2687 (2013).

Romero-Aburto R., Narayanan T.N., Nagaoka Y., Hasumura T., Mitcham T.M., Fukuda T., Cox P.J., Bouchard R.R., Maekawa T., Kumar D.S., Torti S.V., Mani S.A.,* and Ajayan P.M.,* Fluorinated Graphene Oxide; a New Multimodal Material for Biological Applications (2013) Adv Mater. 2013 Oct 18;25(39):5632-7 (*co-corresponding authors)  

Highlighted in Y. H. Hu*, “The First Magnetic-Nanoparticle-Free Carbon-based Contrast Agent of Magnetic Resonance Imaging (MRI)—Fluorinated Graphene Oxide (FGO)”, Small 10, 1451(2014). 

Ling H, Spizzo R, Atlasi Y, Nicoloso M, Shimizu M, Redis R, Nishida N, Gafà R, Song J, Guo Z, Ivan C, Barbarotto E, De Vries I, Zhang X, Ferracin M, Churchman M, van Galen J, Beverloo B, Shariati M, Haderk F, Estecio MR, Garcia-Manero G, Patijn G, Gotley D, Bhardwaj V, Imad S, Sen S, Multani A, Welsh J, Yamamoto K, Taniguchi I, Song MA, Gallinger S, Casey G, Thibodeau S, Marchand LL, Tiirikainen M, Mani S.A., Zhang W, Davuluri R, Mimori K, Mori M, Sieuwerts A, Martens J, Tomlinson I, Neagoe I, Negrini M, Foekens J, Hamilton S, Lanza G, Kopetz S, Fodde R, Calin G. CCAT2, a novel non-coding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer. Genome Res. (2013) 23 (9), 1446-1461.

Zarkoob H., Taube J.H., Singh S.K., Mani S.A., and Kohandel M., Investigating the link between molecular subtypes of glioblastoma, epithelial-mesenchymal transition, and CD133 cell surface protein. PLOS ONE (2013).

Mathkar A., Narayanan T.N., Alemany L.B., Cox P., Nguyen P., Gao G., Chang P., Romero-Aburto R., Mani S.A.,Ajayan P.M., Synthesis of Fluorinated Graphene Oxide and its Amphiphobic Properties. Particle & Particle Systems Characterization. 30 (3), 266-272 (2013)

Lu J., Ye X., Fan F., Xia L., Bhattacharya R., Bellister S., Tozzi F., Sceusi E., Zhou Y., Tachibana I., Maru D.M., Hawke D.H., Rak J., Mani S.A., Zweidler-McKay P., Ellis L.M., Endothelial Cells Promote the Colorectal Cancer Stem Cell Phenotype through a Soluble Form of Jagged-1. Cancer Cell. 23(2):171-85 (2013). 

Hollier B.G., Tinnirello A.A., Werden S.J., Evans K.W., Taube J.H., Sarkar T.R., Sphyris N., Shariati M., Kumar S.V., Battula V.L., Herschkowitz J.I., Guerra R., Chang J.T., Miura N., Rosen J.M., and Mani S.A., FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer. Cancer Research 73(6); 1–12 (2013)

Yao Y., Suraokar M., Darnay B.G., Hollier B.G., Shaiken T.E., Asano T., Chen C.,  Chang B.,  Lu Y.,  Mills G.B., Sarbassov D., Mani S.A., Abbruzzese J.L., Reddy S.A.G. BSTA Promotes mTORC2-Mediated Phosphorylation of Akt1 to Suppress Expression of FoxC2 and Stimulate Adipocyte Differentiation. Sci Signal 6(257)2013. 

2012

Smitha S., Haseena V.S., Narayanan T.N., Reena Mary A.P.,  Ajayan P.M., Puthumana J., Aziz A.A.,  Aburto R.R.,Mani S.A., Joy P.A., and Anantharaman M.R. Fluorescent Superparamagnetic Iron Oxide Core–Shell Nanoprobes for Multimodal Cellular Imaging. Mater. Express, 2 (4), 2012.

Giordano A, Gao H, Anfossi S, Cohen E, Mego M, Lee BN, Tin S, De Laurentiis M, Parker CA, Alvarez RH, Valero V, Ueno NT, De Placido S, Mani S.A., Esteva FJ, Cristofanilli M, Reuben JM. Epithelial-Mesenchymal Transition and Stem Cell Markers in Patients with HER2-Positive Metastatic Breast Cancer. Mol Cancer Ther. 11(11):2526-34 (2012).

Fan F, Samuel S, Evans KW, Lu J, Xia L, Zhou Y, Sceusi E, Tozzi F, Ye X, Mani S.A., Ellis LM. Overexpression ofsnail induces epithelial–mesenchymal transition and a cancer stem cell–like phenotype in human colorectal cancer cells. Cancer Medicine 2012, 1(1) 5-16

Battula VL, Shi Y, Evans KW, Wang RY, Spaeth EL, Jacamo RO, Guerra R, Sahin AA, Marini FC, Hortobagyi G,Mani S.A.*, Andreeff M*. Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis. J Clin Invest. 122(6):2066-78 (2012). (*co-corresponding authors).

Narayanan TN, Gupta BK, Vithayathil SA, Aburto RR, Mani S.A., Taha-Tijerina J, Xie B, Kaipparettu BA, Torti SV, Ajayan PM. Hybrid 2D Nanomaterials as Dual-Mode Contrast Agents in Cellular Imaging. Adv Mater. 24(22):2992-8 (2012). 

Roman-Perez E, Casbas-Hernandez P, Rein J, Carey LA, Lubet RA, Mani S.A., Amos KD, Troester MA, Pirone JR. Gene expression in extratumoral microenvironment predicts clinical outcome in breast cancer patients. Breast Cancer Res 14(2) R51. (2012).

Guo W, Keckesova Z, Donaher JL, Shibue T, Tischler V, Reinhardt F, Itzkovitz S, Noske A, Zürrer-Härdi U, Bell G, Tam WL, Mani S.A., van Oudenaarden A, Weinberg RA. Slug and sox9 cooperatively determine the mammary stem cell state.Cell 148(5):1015-28 (2012).

2011 

Walia V, Yu Y, Cao D, Sun M, McLean JR, Hollier BG, Cheng J, Mani S.A., Rao K, Premkumar L, Elble RC. Lossof breast epithelial marker hCLCA2 promotes epithelial-to-mesenchymal transition and indicates higher risk of metastasis. Oncogene. 31(17):2237-46 (2011). 

Mego, M*., Mani S. A.,* Lee, B., Li, C., Evans, K.W., Cohen, E. N., Gao, H., Jackson, S. A., Giordano, A., Hortobagyi, G. N., Cristofanilli, M., Lucci, A., Reuben, J. M., Expression of Epithelial-Mesenchymal Transition-Inducing Transcription Factors in Primary Breast Cancer: The Effect of Neoadjuvant Therapy, Int. J. of Cancer.130(4):808-16 (2011). (* denotes equal first authors)

Tong Z, Chakraborty S, Sung B, Koolwal P, Kaur S, Aggarwal BB, Mani S.A., Bresalier RS, Batra SK, Guha S. Epidermal growth factor down-regulates the expression of neutrophil gelatinase-associated lipocalin (NGAL) through E-cadherin in pancreatic cancer cells. Cancer. 117;2408-18, (2011).

2010

Taube JH, Herschkowitz JI, Komurov K, Zhou AY, Gupta S, Yang J, Hartwell K, Onder TT, Gupta PB, Evans KW, Hollier BG, Ram PT, Lander ES, Rosen JM, Weinberg RA, Mani S.A., Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci U S A. 107(35):15449-54 (2010). (Cited 502 times as of 7/25/2016 based on Google Scholar)

Battula, V.L., Evans, K.W., Hollier, B.G., Shi, Y., Marini, F.C., Ayyanan, A., Wang, R., Brisken, C., Guerra, R., Andreeff, M., Mani S.A., Epithelial-Mesenchymal Transition-Derived Cells Exhibit Multi-Lineage Differentiation Potential Similar to Mesenchymal Stem Cells. Stem Cells, 28(8):1435-45 (2010). 

2008

Mani S.A.,*,# Guo, W.*, Liao, M.J.,*Eaton E., Ayyanan A.,  Zhou A, Brooks M, Reinhard F., Zhang C., Shipitsin. M., Campbell. L. L., Polyak K., Brisken. C., Yang. J, Weinberg R.A.,# The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell, 133, 704-715. (2008) (*equal first authors & # co-corresponding authors).(Cited 4712 times as of 7/25/2016 based on Google Scholar)

  • Highlighted in New York Times, September 9th, 2008.  Click here to  view. 

  • Highlight by Dr. Robert Weinberg in this short (3 minute) YouTube video 

  • Highlighted in Nature Reviews in Cancer 8, 483 (July 2008).

  • Highlighted in Cell Stem Cell  2 (6):511-2 (June 2008).  

  • Highlighted in Nature Reviews in Mol. Cell Bio. 11, 466 (July 2010).

Bloushtain-Qimron N, Yao J, Snyder EL, Shipitsin M, Campbell LL, Mani S.A., Hu M, Chen H, Ustyansky V, Antosiewicz JE, Argani P, Halushka MK, Thomson JA, Pharoah P, Porgador A, Sukumar S, Parsons R, Richardson AL, Stampfer MR, Gelman RS, Nikolskaya T, Nikolsky Y, Polyak K. Cell type-specific DNA methylation patterns in the human breast. Proc Natl Acad Sci U S A 105 (37):14076-81 (2008).

Onder, T., Gupta, P.B., Mani S.A., Yang, J., Lander, E.S., Weinberg R.A., Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways. Cancer Res 68: 1-10 (2008).  

2007

Mani S.A., Yang, J., Brooks, M., Schwaninger, G., Zhou, A., Miura, N., Kutok, J.L., Hartwell, K., Richardson, A.L., Weinberg, R.A. FOXC2 plays a key role in metastasis and is associated with aggressive basal-like breast cancers. Proc Natl Acad Sci 104:10069-10074 (2007).  (Cited 401 times as of 7/25/2016 based on Google Scholar) 

Liao, M.J., Zhang, C.C., Zhou, B., Zimonjic. D.B., Mani S.A., Lodish, H.F., Weinberg, R.A. Enrichment of a population of mammary gland cells that forms mammospheres and has in vivo repopulating activity. Cancer Research67:8131-8138, (2007).  

2004 & Earlier

Yang, J*., Mani S.A*., Donaher, J.L., Ramaswamy, S., Itzykson, R.A., Come, C., Savagner, P., Gitelman, I., Richardson, A., and Weinberg, R.A. Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis. Cell 117:927–939, (2004). (*Denotes equal first authors). (Cited 2735 times as of 7/25/2016 based on Google Scholar)  

Samudre, K.R., Mani S.A., Vathsala, P.G., Rangarajan, P.N., Padmanaban, G. Phenobarbitone-mediated translocation of the cytosolic proteins interacting with the 5′-proximal region of rat liver CYP2B1/B2 gene into the nucleus. BBRC,292:312-7, (2002). 

Harish S., Khanam, T., Mani S.A., and Rangarajan, P.N. Transcriptional activation by hepatocyte nuclear factor-4 in acell-free system derived from rat liver nuclei. Nucleic Acids Res 29:1047-53, (2001).

Mani S. A., Harish, S., Vathsala, P.G., Rangarajan, P.N., and Padmanaban, G. Receptor-mediated gene delivery demonstrates the role of 5′ proximal DNA region in conferring phenobarbitone responsiveness to CYP2B1/B2 gene in rat liver in vivo. Biochem Biophys Res Commun 268:734-739, (2000). 

Fernandez, M.A., Mani S.A., Rangarajan, P.N., and Seshagiri, P.B. Sperm-mediated gene transfer into oocytes of golden hamster: Assessment of sperm function. Indian Journal of Experimental Biology 37:1085-1092, (1999).

Prabhu, L., Upadhya, P., Ram, N., Nirodi, C. S., Sultana, S., Vatsala, P. G., Mani S.A., Rangarajan, P. N., Surolia, A., Padmanaban, G. A model for the transcriptional regulation of the CYP2B1/B2 gene in rat liver. Proc Natl Acad Sci USA92:9628-963, (1995). 

 

Invited Articles 

 

Pietila M., Ivaska J., Mani S.A., Whom to blame for metastasis, the epithelial-mesenchymal transition or the tumor microenvironment? Cancer Letters 2016

Sphyris N., Sarkar T.R., Battula V.L., Andreeff M., Mani S.A., GD2 and GD3 synthase: novel drug targets      forcancer therapy. Molecular & Cellular Oncology, 2-3, (2015).

Barsan, V., Cristofanilli, M., Mani S.A., Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition, Breast Diseases, Volume 24, Issue 3, 2013, Pages 225-226

Chang J.T., Mani S.A., Sheep, Wolf, or Werewolf: Cancer Stem Cells and the Epithelial-to-Mesenchymal Transition,Cancer Letters (2013) 341(1), 16-23   

Kolonin MG, Evans KW, Mani S.A., Gomer RH. Alternative origins of stroma in normal organs and disease. Stem Cell Res. 8 (2) 312-323 (2011).  

May, C. D., Sphyris, N., Evans, K.W., Werden, S.J., Guo, W., Mani S.A., Epithelial–mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression, Breast Cancer Research. 13 (1), 202 (2011).

Mego M, Mani S.A., Cristofanilli M. Molecular mechanisms of metastasis in breast cancer — clinical applications. Nat Rev Clin Oncol. 7 (12):693-701 (2010). 

Blick T, Hugo H, Widodo E, Waltham M, Pinto C, Mani S. A, Weinberg RA, Neve RM, Lenburg ME, Thompson EW. Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer. J Mammary Gland Biol Neoplasia. 15(2):235-52 (2010).

Sphyris N., Mani S. A., The Importance of the Epithelial–Mesenchymal Transition in Breast Cancer, Current Breast Cancer Reports (2009) 1:229–237. 

Lu J, Steeg PS, Price JE, Krishnamurthy S, Mani S.A, Reuben J, Cristofanilli M, Dontu G, Bidaut L, Valero V, Hortobagyi GN, Yu D. Breast Cancer Metastasis: Challenges and Opportunities. Cancer Research  69: (12)-4951. (2009).

Mani S.A., Evans, K.W., Hollier, B.G., Guo, W., Weinberg, R.A., Generation of Stem-like Cells via EMT: A New Twist in Cancer Initiation and Progression. AACR education book, (1): 173. (2009).

Hollier, B.G., Evans K.W., Mani S.A., The Epithelial-to-Mesenchymal Transition and Cancer Stem Cells: A Coalition Against Cancer Therapies. Journal of mammary gland biology and neoplasia, 14, (1): 29, (2009).

Gupta, P., Mani S.A., Yang, J., Hartwell, K., Weinberg, R.A. The evolving portrait of cancer metastasis. Cold Spring Harbor Symposia on Quantitative Biology 70:291-298, (2005).

Yang, J., Mani S.A., and Weinberg, R.A. Exploring a New Twist in Tumor Metastasis. Cancer Res 66:1-3, (2006).

 

Editorials

 

Francastel C., Hubé F., Mani S.A., Santulli G., Taube J.H., Szweykowska-Kulinska Z., The Non-Coding RNA Journal Club: Highlights on Recent Papers—2, Non-Coding RNA 2015, 1, 167-169.

Ferracin M., Gautheret D., Hubé F., Mani S.A., Mattick J.S., Ørom U.A., Santulli Q., Slotkin R.K., Szweykowska-Kulinska Z., Taube J.H., Vazquez F., Yang J., The Non-Coding RNA Journal Club: Highlights on Recent Papers, Non-Coding RNA 2015, 1, 87-93.

Mani S.A., Barton M. C., HDAC3 at the Fulcrum of an Epithelial-Mesenchymal Balance, Mol. Cell, 43 (5): 697-698 (2011).

Sphyris N, Mani S.A., pIgR: Frenemy of Inflammation, EMT, and HCC Progression, J Natl Cancer Inst 103 (22) 1644-45 (2011) 

 

Book Chapters

 

Taube J., Mani S. A., Epithelial-to-mesenchymal transition, stem cells, and cancer progression. NOVA publishers book on “Stem Cell, Regenerative Medicine and Cancer” (2010).